One of the most significant global public health challenges is antimicrobial resistance (AMR). Improper use of antibiotics is among the leading causes of drug resistance to various substances. In Eastern Iran's Mashhad, a tertiary hospital has undertaken research on antibiotic usage and bacterial resistance patterns for three years, as part of a regional action plan to combat healthcare-associated illnesses. The Ghaem hospital's pharmacy and microbiology lab have diligently collected information on antibiotic use and bacterial resistance over this period. The data revealed that Meropenem, Ceftriaxone, and Ciprofloxacin were the most frequently used antibiotics in 2017, 2018, and 2019, respectively. Between 2017 and 2019, E. coli, A. baumannii, and K. pneumonia exhibited significant changes in their resistance rates (RR) to various antibiotic classes, with the exception of Imipenem. Notably, S. aureus displayed declining trends in Ciprofloxacin RRs. Our findings indicate a reduction in the use of several antibiotics at Ghaem hospital during this period, while Metronidazole, Imipenem, and Cefepime remained preferred choices. The overuse of broad-spectrum antimicrobials has resulted in serious public health issues. Hence, continued efforts are essential to optimize antibiotic administration, mitigate antibiotic resistance, and gather additional data for policy-making.
| Published in | Journal of Health and Environmental Research (Volume 9, Issue 4) |
| DOI | 10.11648/j.jher.20230904.11 |
| Page(s) | 95-99 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2023. Published by Science Publishing Group |
Antibiotics, Antimicrobial Resistance, Multidrug-Resistant, Resistance Rates
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APA Style
Hasanzadeh, S., Mehri, A., Sadat Shahabifar, M., Ghazvini, K. (2023). Antibiotic Consumption and Bacterial Resistance Pattern During Three Years at a Tertiary Hospital in Mashhad, Eastern Iran. Journal of Health and Environmental Research, 9(4), 95-99. https://doi.org/10.11648/j.jher.20230904.11
ACS Style
Hasanzadeh, S.; Mehri, A.; Sadat Shahabifar, M.; Ghazvini, K. Antibiotic Consumption and Bacterial Resistance Pattern During Three Years at a Tertiary Hospital in Mashhad, Eastern Iran. J. Health Environ. Res. 2023, 9(4), 95-99. doi: 10.11648/j.jher.20230904.11
AMA Style
Hasanzadeh S, Mehri A, Sadat Shahabifar M, Ghazvini K. Antibiotic Consumption and Bacterial Resistance Pattern During Three Years at a Tertiary Hospital in Mashhad, Eastern Iran. J Health Environ Res. 2023;9(4):95-99. doi: 10.11648/j.jher.20230904.11
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Download@article{10.11648/j.jher.20230904.11,
author = {Sepideh Hasanzadeh and Ali Mehri and Mahin Sadat Shahabifar and Kiarash Ghazvini},
title = {Antibiotic Consumption and Bacterial Resistance Pattern During Three Years at a Tertiary Hospital in Mashhad, Eastern Iran},
journal = {Journal of Health and Environmental Research},
volume = {9},
number = {4},
pages = {95-99},
doi = {10.11648/j.jher.20230904.11},
url = {https://doi.org/10.11648/j.jher.20230904.11},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jher.20230904.11},
abstract = {One of the most significant global public health challenges is antimicrobial resistance (AMR). Improper use of antibiotics is among the leading causes of drug resistance to various substances. In Eastern Iran's Mashhad, a tertiary hospital has undertaken research on antibiotic usage and bacterial resistance patterns for three years, as part of a regional action plan to combat healthcare-associated illnesses. The Ghaem hospital's pharmacy and microbiology lab have diligently collected information on antibiotic use and bacterial resistance over this period. The data revealed that Meropenem, Ceftriaxone, and Ciprofloxacin were the most frequently used antibiotics in 2017, 2018, and 2019, respectively. Between 2017 and 2019, E. coli, A. baumannii, and K. pneumonia exhibited significant changes in their resistance rates (RR) to various antibiotic classes, with the exception of Imipenem. Notably, S. aureus displayed declining trends in Ciprofloxacin RRs. Our findings indicate a reduction in the use of several antibiotics at Ghaem hospital during this period, while Metronidazole, Imipenem, and Cefepime remained preferred choices. The overuse of broad-spectrum antimicrobials has resulted in serious public health issues. Hence, continued efforts are essential to optimize antibiotic administration, mitigate antibiotic resistance, and gather additional data for policy-making.
},
year = {2023}
}
TY - JOUR T1 - Antibiotic Consumption and Bacterial Resistance Pattern During Three Years at a Tertiary Hospital in Mashhad, Eastern Iran AU - Sepideh Hasanzadeh AU - Ali Mehri AU - Mahin Sadat Shahabifar AU - Kiarash Ghazvini Y1 - 2023/11/24 PY - 2023 N1 - https://doi.org/10.11648/j.jher.20230904.11 DO - 10.11648/j.jher.20230904.11 T2 - Journal of Health and Environmental Research JF - Journal of Health and Environmental Research JO - Journal of Health and Environmental Research SP - 95 EP - 99 PB - Science Publishing Group SN - 2472-3592 UR - https://doi.org/10.11648/j.jher.20230904.11 AB - One of the most significant global public health challenges is antimicrobial resistance (AMR). Improper use of antibiotics is among the leading causes of drug resistance to various substances. In Eastern Iran's Mashhad, a tertiary hospital has undertaken research on antibiotic usage and bacterial resistance patterns for three years, as part of a regional action plan to combat healthcare-associated illnesses. The Ghaem hospital's pharmacy and microbiology lab have diligently collected information on antibiotic use and bacterial resistance over this period. The data revealed that Meropenem, Ceftriaxone, and Ciprofloxacin were the most frequently used antibiotics in 2017, 2018, and 2019, respectively. Between 2017 and 2019, E. coli, A. baumannii, and K. pneumonia exhibited significant changes in their resistance rates (RR) to various antibiotic classes, with the exception of Imipenem. Notably, S. aureus displayed declining trends in Ciprofloxacin RRs. Our findings indicate a reduction in the use of several antibiotics at Ghaem hospital during this period, while Metronidazole, Imipenem, and Cefepime remained preferred choices. The overuse of broad-spectrum antimicrobials has resulted in serious public health issues. Hence, continued efforts are essential to optimize antibiotic administration, mitigate antibiotic resistance, and gather additional data for policy-making. VL - 9 IS - 4 ER -
Antimicrobial Resistance Research Centre, Mashhad University of Medical Sciences, Mashhad, Iran; Department of Microbiology and Virology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
